It may miss some mutations that close to the downstream EBE site.
Because of its recent appearance, K166Q is a mutation that requires close examination, particularly regarding vaccine efficacy.
In stocks carrying a suppressor mutation that mapped very close to the RFP insertion at 85E (only 1-3% recombination frequency between suppressor mutation and RFP at 85E), and therefore also close to Df 3R Exel6149 at 85A, the Mkk4 gene was checked for point mutations by sequencing.
The R403Q mutation is the most widely studied FHC-related mutation that is located in close proximity to the actin-binding interface of myosin.
These data resolved the presence of a mutation that confers CQ-R, close to nucleotide 1,000,000 on chr11.
First, mutations that are closer together, as is the case with the two mutations identified by Ellison and Bachtrog, can be transferred simultaneously.
Thus, while there may not be a close correlation, the mutation that reduces production of carotenoids in carrot roots may also inhibit tocochromanol accumulation.
STE5 and ARO1 each bear a second silent mutation that may be present due to close genetic linkage to the productive mutation or lead to a non-obvious phenotypic modification, such as altered mRNA stability, and thereby arise in R57 through selection.
She has a gene mutation that caused tuberous sclerosis.
One category of mutations produces a protein that is able to insert itself into the membrane of the cell but contains a "rusty gate" that closes off the passage of chloride.
