Sentence examples for mutants suggested a from inspiring English sources

Several phenotypes associated with these mutants suggested a defect in SPB duplication.

The finding of polydactyly in the Mks1 mutants suggested a defect in Shh signaling, because Shh is required for normal anterior-posterior patterning of the limb bud.

Our previous electron microscopic studies and biochemical analyses of the cell wall of ccw12Δ mutants suggested a crucial structural role for Ccw12p during vegetative cell growth [ 11, 12].

Preliminary analysis of mice that lacked all 3 neuronal Robo receptors (Robo1/2/3 triple mutants) suggested a marked reduction in the number of interneurons in the developing cortex, but only a limited effect on their morphology.

The unexpectedly high representation of members of this superfamily of plasma membrane-localized proteins in genes upregulated in CrebA mutants suggested a potential link to the excessive SJ membrane phenotype (Table 1).

The close phenotypic resemblance of Nde1+/−Lis1+/− and Nde1−/− mutants suggested a dose-dependent genetic interaction of Nde1 with Lis1, and that the two genes function in a common molecular pathway regulating cerebral cortical development.

In contrast, the inhibitory effects of TGFbRII and ACTRIIA mutations were only observed in the cells stably expressing the receptor mutants, suggesting a possibly involvement of other unidentified mechanisms that require further investigation.

The similarities of tracheal and salivary gland phenotypes in γCOP mutants suggest a common cellular mechanism expanding tubular organs.

In addition, abnormal circadian periods in clock mutants suggest a common molecular machinery responsible for circadian rhythmicity.

SRO7 was initially isolated as a high-copy suppressor of rho3 mutants, suggesting a role for Sro7p in maintenance of actin polarity [20], [21].

In contrast to wild-type fish, a comparison of 1- and 2-year old ACHE mutants suggests a delay in the onset of cognitive aging.