Sentence examples for mutants indicate a from inspiring English sources

Moreover, experiments with flotillin mutants indicate a Golgi-dependent transport of flotillin-2 and a similar trafficking for flotillin-1 [11].

In mice, knock-out mutants indicate a redundancy among MMPs and only few MMPs have been found to be required specifically during bone and vascular remodeling and mammary development [2], [6].

These findings, together with the aberrant tendency for swollen knobs to protrude above the ciliary layer in the MKS3 mutants, indicate a defect in the maturation process of OSNs, and consequently a flaw in either the initial organization, or in the maintenance, of the OE.

The pleiotropic tissue outgrowth defects in Prickle1 mutants indicate a disruption of PCP pathway that govern morphogenesis.

The observed mating and agglutination defects of ccw12Δ mutants indicate a role of CCW12 in conjugation [ 7].

Further, responses of key mutants indicate a probable commonality in mode of action of both IXB and TA, distinct from DCB which appears to be more distantly related.

Experiments using NICD1 deletion mutants indicated a role for the RAM domain in this process, and either Jagged1 stimulation or expression of a transcriptionally active form of RBP-J in 32D cells also promoted myeloid differentiation (Schroeder and Just, 2000).

Under these conditions, the wild type strain and the bat1Δ mutant showed higher growth rates than those observed in the double and bat2Δ mutants indicating a catabolic role for Bat2 (Table 2 and Figure 1B, CEN).

The mRNA levels of several G1, but not G2, regulators change in scr mutants, indicating a peculiar role of G1 regulators in the RBR/SCR-mediated pathway that controls stem cell maintenance [73].

As loss of branch point C function alone (lane 4) results in only partial exclusion of exon five from BAX mRNA, the near total skipping of exon five seen with these potentially compound mutants indicates a significant contribution of the polypyrimidine tract to correct BAX splicing.

Similarly, copulation attempts were absent in Est-6° mutants, indicating a decrease in courtship vigor.