Sentence examples for mutants indicates a from inspiring English sources

As loss of branch point C function alone (lane 4) results in only partial exclusion of exon five from BAX mRNA, the near total skipping of exon five seen with these potentially compound mutants indicates a significant contribution of the polypyrimidine tract to correct BAX splicing.

Since ATG2 is autophagy-specific, the powdery mildew-induced cell death of susceptible Arabidopsis atg2 mutants indicates a pro-survival role of autophagy in this compatible interaction [ 55].

The analysis of dusp6:dGFP in fgf8a mutants indicates a transcriptional response to Fgf signaling in the endoderm that, at least in part, requires mesodermal Fgf8a.

But in mature leaves, the presence of smaller cells with lower CV of cells in ccs52a2 mutants indicates a role for CCS52A2 in these tissues.

Experiments using NICD1 deletion mutants indicated a role for the RAM domain in this process, and either Jagged1 stimulation or expression of a transcriptionally active form of RBP-J in 32D cells also promoted myeloid differentiation (Schroeder and Just, 2000).

Moreover, experiments with flotillin mutants indicate a Golgi-dependent transport of flotillin-2 and a similar trafficking for flotillin-1 [11].

Under these conditions, the wild type strain and the bat1Δ mutant showed higher growth rates than those observed in the double and bat2Δ mutants indicating a catabolic role for Bat2 (Table 2 and Figure 1B, CEN).

In mice, knock-out mutants indicate a redundancy among MMPs and only few MMPs have been found to be required specifically during bone and vascular remodeling and mammary development [2], [6].

The mRNA levels of several G1, but not G2, regulators change in scr mutants, indicating a peculiar role of G1 regulators in the RBR/SCR-mediated pathway that controls stem cell maintenance [73].

These findings, together with the aberrant tendency for swollen knobs to protrude above the ciliary layer in the MKS3 mutants, indicate a defect in the maturation process of OSNs, and consequently a flaw in either the initial organization, or in the maintenance, of the OE.

Similarly, copulation attempts were absent in Est-6° mutants, indicating a decrease in courtship vigor.