Finally, C. elegans exhibit a form of long-term memory in response to repetitive mechanical stimulation that requires GLR-1 [19]; we find that both GLR-2 and MAGI-1L mutants share a similar defect in long-term memory acquisition.
Both haploid and diploid ccr4Δ strains are sensitive to S phase specific DNA damaging agents such as HU, indicating that CCR4 haploid and diploid mutants share a common checkpoint repair defect that extends into S phase.
Furthermore, agmo-1 and the BH4-deficient mutants share a common phenotype of sensitivity to bacterial infection by Leucobacter Verde1.
Because dachs and ft dachs mutants share a similar phenotype, the defect in Fz-EYFP localization is likely due to the lack of Dachs.
This is absolutely in line with our observation that the three mutants share a common signalling pattern which is independent of the location of the mutation within the receptor chain.
cycd3;1, ant and cytokinin biosynthesis and receptor mutants share a common failure in cambial proliferation, and we show that these components act in conserved pathways linking cytokinins to developmentally regulated cell proliferation.
In studies of WT and mutant SOD1 expressed in cultured cells, our studies reported here, and previously [ 27], indicate that the C4F6 antibody can be used to detect misfolded mutant SOD1 and that most if not all fALS mutants share a common misfolded conformation around the loop between 90 93.
Given that the rpl24b mutant shared a common set of translationally stimulated and translationally inhibited mRNAs with eif3h, we examined whether these mRNAs harbored the same features that render some Arabidopsis mRNAs eIF3h-dependent.
Both mutants share an increased exposure of M213 and for R208H also of M205, suggesting that under an oxidative environment the α3 methionines could exist as sulfoxides [Figure 4].
Of these, nrf-5, nrf-6, and ndg-4 define a subclass of Nrf mutants sharing an additional second phenotype of producing pale eggs with fewer yolk granules.
