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To assess cell-autonomy of ptenb function in mediating migration of lateral hypoblast cells, we performed cell transplantation experiments by using rhodamine dextran as a cell tracer.
Structurally distinct from other cellular connections, the first type of EP bridge may mediate transport of cellular material between cells, while the second type of EP bridge is functionally distinct from all other cellular connections by mediating migration of epithelial cells between EP masses.
It has remained, however, unknown whether and how VEGF-C-binding receptors participate in mediating migration of VEGF-C-producing breast cancer cells.
Notwithstanding, these results suggest a unique signaling crosstalk between Rho/ROCK and ERK in mediating migration of VSMCs induced by ADMA.
To identify a signalling network mediating migration of pancreatic cancer cells by secreted SEMA5A, we examined ERK phosphorylation after treatment with recombinant Sema5A-ECD.
Similar(54)
Given that we found attenuated CXCL1 message in the TNFR2 deficient mice and decreased numbers of OPCs within the CC, these data suggest that TNFR2 signaling may mediate migration of OPCs via CXCL1 signaling.
Chemokines are members of a superfamily of small polypeptides mediating migration, growth and activation of leukocytes and a variety of other cells [ 31].
MYLK is associated with breast tumor metastasis through in vitro studies showing its role in mediating migration and invasion of the MDA-MB-231 cell-line [ 51] and the intravasation of breast cancer cells through an endothelial cell layer [ 52].
We determined that Stat3 deficient Ras transformed MCF10A cells were less capable of mediating migration, invasion and tumorigenesis than the control MCF10A-Ras cells.
Therefore, FLJ10540 seems to mediate migration and invasion effects of VEGF-A independently of EMT and does not appear to play a role in the regulation of EMT, at least in the lung cancer cell lines we analyzed.
The molecular mechanism that underlies GM3 synthase mediated migration and invasion was inhibition of the phosphoinositide-3 kinase/Akt pathway.
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