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Further, PIM was suggested to act as adhesins mediating attachment of M. tuberculosis bacilli to non-phagocytic cells [27].
GOAT is the transferase mediating attachment of octanoate to the appetite-stimulating hormone proghrelin [30], [37] [39].
The kinetochore (KT) is the protein complex responsible for mediating attachment of sister chromatids to the mitotic spindle and for directing chromosome movements during mitosis.
Both of these molecules belong to immunoglobulin supergene family mediating attachment of leukocytes to vascular endothelium and their trans-endothelial migration, thereby having an important influence on inflammatory reactions (Muller 2009).
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Integrin αvβ3 was proposed to mediate attachment of Pam3CSK4 to cell surfaces through binding of vitronectin attached to the lipopeptide.
It is tempting to speculate that integrin αvβ3 is responsible for attachment of Pam3CSK4 to the surface of the macrophages, since integrin αvβ3 was previously proposed to mediate attachment of Pam3CSK4 to cell surfaces [10].
It also mediates attachment of the adhesin Cpa at the tip of the pilus [46] and attachment of the pilus shaft to the basal pilin Spy0130 [47], in each case through amide bond formation.
Furthermore, HWP1 up-regulation may also increase adhesion since Hwp1p is a glycosylphosphatidylinositol cell wall adhesin (GPI-CWP) and mediates attachment of C. albicans cells to human endothelial and epithelial cells [44].
To date, the most prominent model holds that upon activation via TRAF6 homo-oligimerization, the RING finger ubiquitin E3 ligase domain complexes with a K63-specific E2 conjugating enzyme (Ubc13/Uev1a, or possibly UbcH7) to mediate attachment of non-degradative K63-linked ubiquitin chains to TRAF6 substrates, specifically TRAF6 itself [4], [16].
PilC1 is an adhesin that mediates attachment of N. meningitidis to host cells.
It is hypothesized that the Ndc80 complex directly mediates attachment of kinetochores to spindle microtubules (Cheeseman et al. 2006; Wei et al. 2007; Deluca et al. 2006).
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