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It is likely that a combined regulatory effect of IFN-γ and NO may be directly involved in mediating suppression of target cells and inhibition of diabetes by NR286 Treg cells.
These data demonstrate that IFG exerts in vivo effects by enhancing V394L GCase protein and activity levels, and in mediating suppression of proinflammation, which led to delayed onset of neurological disease and extension of the life span of 4L C* mice.
Fractionation of 'exosomes' revealed two distinct fractions mediating suppression of CD3- ζ: 26 and 42 kDa.
'Exosome' components mediating suppression of CD3- ζ were isolated by continuous eluting electrophoresis and examined by Western immunoblotting.
Foxp3 serves as a specific lineage transcript factor in Treg cells in mediating suppression of lymphocyte proliferation.
Likewise, ABA-treated seeds of an Arabidopsis mutantof PICKLE (a chromatin remodelling factor mediating suppression of embryonic identity upon germination) showed high expression levels of the ABA-induced transcription factors, ABI3 and ABI5, involved in seed filling.
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The HVS-transformed cells provide a useful tool for the study of noncytolytic CD8+ T lymphocyte-mediated suppression of HIV-1.
Likewise, IDO can mediate suppression of T-cell immunity to MHC-mismatched liver allografts [3].
Given these data, it is possible that ERα46 mediates suppression of CXCL8 transcription via suppression of ERα66.
In vivo LAP utilized an IL-10-dependent pathway to mediate suppression of the cellular immune response.
Malaria could cause anemia through cytokine mediated suppression of haematopoiesis or by predisposing the victim to other infection [5], [28].
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mediating folding of
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