Sentence examples for mediating transport of from inspiring English sources

These transporters are ATP-dependent drug efflux pumps mediating transport of endogenous and xenobiotic substances.

FcRn also contributes to passive immunity by mediating transport of IgG from mother to fetus (human) or newborn (rodents), and may translocate IgG over mucosal surfaces.

Overall these findings implied that two distinct connections between EP islands existed: the first being simple, tubular connections possibly mediating transport of cellular material between two cells (type I); and the second being complex, tubular connections facilitating migration of entire cells between multi-cellular EP islands (type II).

The first type of EP bridge may be functionally similar to cytonemes and TNTs by possibly mediating transport of cellular material between cells, while the second type of EP bridge is distinct in function compared to cytonemes and TNTs by facilitating the migration of entire cells between EP masses.

ERVK-17 is located intronically in antisense orientation in the MRP2 gene, a member of the MRP subfamily, mediating transport of anticancer agents and contributing to drug resistance (Kruh and Belinsky 2003).

Our findings that siRNA loss of calsyntenin-1 reduces axonal transport of APP and increases APP levels in the TGN are thus consistent with a role for calsyntenin-1 in mediating transport of APP on post-Golgi carriers.

In particular, the plasmodial hexose transporter, PfHT, known to mediate transport of this essential substrate to the parasite has been a promising candidate for development of inhibitors.

FcRn also mediates transport of intact IgG across polarized epithelial barriers, a pathway that is attractive for delivery of Fc-containing therapeutics.

B. anthracis produces two binary exotoxins, lethal (LT) and edema toxins (ET) [9-11], eaconsistinging of a toxic moiety [lethal factor (LF) and edema factor (EF), respectively] and protective antigen (PA), which mediates transport of the toxic moieties into host cells.

After phagocytosis, NRAMP1 is targeted to the membrane of the microbe-containing phagosome, where it mediates transport of iron and other cations.

The gene glpT belongs to the organophosphate:phosphate antiporter family of the major facilitator superfamily (MFS); it mediates transport of glycerol 3-phosphate (G3P) across the membrane in bacteria [43].