Sentence examples for marked cell cycle from inspiring English sources

Finally, we identified that p38γ MAPK overexpression led to marked cell cycle arrest in G2/M phase.

Results of this study clarified that AgNPs induced cell cycle arrest at G1, while a combined treatment of AgNPs with irradiation induced marked cell cycle arrest at S, G2/M phases.

G0/G1 arrest is one of the marked cell cycle features of senescent cells and thus our results indicate that E2 + TNF-α combination resulted in enhanced survival by forcing cells towards senescence.

For example, a concentration of 10 n M Aplidine for 1 h caused no detectable inhibition of total proteins, RNA or DNA synthesis but did cause marked cell cycle perturbations and cytotoxicity.

In exponentially growing cells Ki-S1 showed a marked cell cycle phase-specific variation in staining intensity which increased linearly through the S-phase, was high in G2 and reached its peak in mitosis.

Further, the cell cycle analysis in mimic-transfected RB cells pointed to a marked change in the G2/S phase of the Y79 cells (∼48.7% and 48.7%), and the scramble mimic treatment resulted in 30.5% of G2/S phase of cell cycle, while no marked cell cycle phase was observed in mimic-transfected Weri Rb 1 cells (Fig. 7).

KYSE450 is the most sensitive cell line as evaluated by MTT assay and showed marked cell-cycle arrest in G2/M phase.

Cell cycle analyses at day 7 identified a marked G1 cell cycle arrest in those cell lines that displayed differentiation in response to B/M (data not shown).

This was significant only for one term for the H3K4me3-marked genes; cell cycle (FDR < 0.001; Additional file 6).

Treatment of PC12 cells with NGF induces differentiation into neuron-like cells marked by cell cycle arrest and neurite extension [ 35] along with marked changes in gene expression [ 36] and signaling pathway activity [ 37].

CRISPR/Cas9-mediated knock-in of Rpt3-T25A mutation, which reduces endogenous proteasome activity, causes marked accumulation of cell cycle inhibitors such as p21Cip1 and p27Kip1 during S-to-G2/M transition and impedes cell proliferation.