Sentence examples for marked cell death from inspiring English sources
After 24 h of exposure, streptomycin caused marked cell death (>2 lof10) of the 1-month-old cultures, with cell survival of 0.23% ± 0.1%.
Constitutive depletion of the mouse HIF1α gene (HIF1α−/−) results in developmental arrest and embryonic lethality, which is characterized by neural tube defects, cardiovascular malformations, dysregulated erythropoiesis signaling, and marked cell death within the cephalic mesenchyme.
Similarly, siGlut-1 interference did not re-establish siHIPK2 cell death under glucose restriction, whereas marked cell death was reached only after zinc supplementation, a condition known to reactivate misfolded p53 and inhibit the pseudohypoxic phenotype in this setting.
HIPK2 silencing impaired RKO colon cancer cell death under limiting glucose availability or under inhibition of glucose metabolism by 2-deoxy-𝒟-glucose (2-DG), compared with HIPK2-proficient cells that instead underwent marked cell death.
In our study, knockdown of Hsp27 in breast cancer cells did not induce marked cell death at 48 h, which was the time point at which we analyzed the ALDH+ population in both AS-B145 and AS-B244 cells, but slowed the cell growth (Additional file 1 Figure S3).
Notably, the combined knockdown of XIAP and c-FLIP was sufficient to cause marked cell death in NSCLC H460 and H661, even in the absence of exogenous TNF α, suggesting a heightened reliance on XIAP and c-FLIP for survival in certain cancer cells.
To determine if the defects observed in the tails of sept9a_tv1 morphant and overexpression (OE) embryos included an increase in apoptotic cells, we used acridine orange (AO) to mark cell death.
Early stages of strokes, which show a diffuse myelin pallor and preserved axons also display marked neuronal cell death in the affected cortex areas and/or an invasion of granulocytes; neither finding is observed in MS lesions.
AV accumulation precedes ΔΨ m loss, which marks imminent cell death and apoptosis.
As well as, Fig. 3 reveals that there are marked increases in cell death after 48 h incubation with ZnO NPs, under the fluorescence microscope.
However, adding C6-ceramide led to a very pronounced increase in ceramide level and marked increase in cell death.
