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The marked cell shrinkage observed with Arsenate and Cadmium was followed by an increase in Cell Roundness at the late 100 µM dose particularly with cadmium (figure 3c).
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In addition to vacuolization, tapetal cell deterioration is marked by cell shrinkage, polarization of cytoplasmic material, thinning of cell walls that become less distinct between adjacent cells, and DNA fragmentation.
Fluorescent assays revealed characteristic apoptotic features, including cell shrinkage, nuclear condensation, and marked decrease in mitochondrial membrane potential in SF-3 treated cells.
Visual inspection of cells marked with a cotransfected GFP construct showed that this gene induced cell shrinkage and membrane blebbing, both typical features of apoptotic cells (Fig. 1 B,C ).
Of note, no RVI followed hypertonicity-induced cell shrinkage when STS was present.
Visual inspection by phase-contrast microscopy revealed the onset of cell shrinkage and cytoplasmic condensation upon treatment of promastigotes with OC (100 μg ml-1), marked by complete circularization of almost all the cells at 96 h post-treatment.
Minor cell shrinkage was observed.
q Dyad stage, cell shrinkage.
s Tetrad stage, cell shrinkage.
r Dyad stage, cell shrinkage.
l Tetrad stage, cell shrinkage.
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