Sentence examples for binding sites generated by from inspiring English sources

Among the hundreds of overlaid binding sites generated by MED-SuMo, we found the protein-ligand complexes overlaid by Pierce et al. [3] for ligand hybridization in the BREED method.

To guide mapping of the potentially ligandable binding sites of the structural proteome, an exhaustive all-against-all BSC was performed on the Pilot dataset containing 2708 binding sites generated by fpocket.

Discrimination of direct versus indirect effects is a limitation of these experiments however this may be overcome by applying computational models of consensus binding sites generated by CLIP or SELEX to classify global changes in alternative splicing [39], [41].

cDNMT3B 3'UTR and cDNMT3B 3'UTR mutants for each miRNA binding sites generated by point mutation cloned into a pcDNA3 plasmid encoding eGFP and cDNMT3B 3'UTR-specific miRNAs including gga-miR-15c, gga-miR-29b, gga-miR-383, and gga-miR-222 cloned into a pDsRed2-N1 plasmid, respectively, encoding RFP were cotransfected into 293 FT cells.

The asymmetry produced by the bending is likely to distort remaining binding sites generated by the inherent three-fold symmetry, accounting for the observation that a maximum of two N-CEACAM1 molecules readily associate with each UspA1 trimer.

Functional antibodies were obtained from a library of antigen-binding sites generated by a binary code restricted to tyrosine and serine.

We will also study generalized models with correlations between two sites generated by cooperative binding.

The plasmid containing site-directed mutations in putative p53 binding sites was generated by replacing the wild type Mlu I- Xho I fragment of pGL2-210 with a mutant fragment synthesized artificially pGL2-210BB, Table 1, Fig. 3).

Mutations in the miR-200c binding sites were generated by PCR directed mutagenesis.

The reporter constructs containing various lengths of Fra-1 promoter or mutated STAT3 binding sites were generated by subsequent PCR-based cloning.

In the next step (see Figure 1), sequence based predictions for transcription factor binding sites are generated by PoSSuM [ 10], in particular based on the JASPAR position specific scoring matrix database [ 21].