Sentence examples for binding sites recognized by from inspiring English sources

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Dr. Law said that the variant segment linked to schizophrenia had a single DNA unit change at the center of one of the binding sites recognized by the transcription factors that control the gene.

Although the exact mechanisms responsible for thrombocytopenia after GP IIb-IIIa blockade are poorly understood, an immune mechanism is suggested in which the binding of the antagonist to GP IIb-IIIa receptors leads to the exposure of ligand-induced binding sites recognized by preexisting or induced antibodies.

Since the binding sites recognized by Adr1 and Cat8 are very dissimilar, the possibility that stable PIC formation requires the DNA to be bound at two positions or by two separate factors at these promoters is ruled out.

A DNA element derived from the pOPI3CAT expression vector containing three symmetric lac operator (lacO) binding sites recognized by the lac repressor (lacI), within a SV40-derived intron, was subcloned between the transcription start site of the endogenous Vav-gene and the multiple cloning site (MCS) of the HS21/45 VavP-transgenic vector.

Different EpoR isoforms and specific binding sites recognized by the antibodies used in the present study.

Here we have identified potential target genes with well-described DNA binding sites recognized by the -KTS isoform and have not assessed the less well understood RNA binding sites recognized by the +KTS isoform [ 60].

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Similar(46)

First, computational analysis has revealed that the ALK binding site recognized by β-catenin substantially overlaps with that of crizotinib22.

The amino-terminal tyrosine (Tyr) 397 residue of FAK, whose autophosphorylation leads to full FAK activation, creates a high-affinity binding site recognized by the SH2 domain of the Src family.

Besides the co-factors presented above, a predominantly occurring motif is similar to a binding site recognized by Sp1 (Specificity protein 1), a transcription regulator that plays a role in TGF beta induced cell migration and mesenchymal transition, regulates angiogenesis, heart contraction, and aberrant expression is associated with several types of cancer.

This demonstrates that optimal bortezomib-induced activation of MMP-1 transcription requires an AP-1 binding site recognized preferentially by a c-Jun/c-Fos heterodimer.

Ancestral binding sites as well as novel binding sites are recognized by the heterozygous population, which therefore experience no deleterious effects from mismatch binding, and at the same time benefit from improved binding with the novel variant.

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