Sentence examples for binding sites characterized by from inspiring English sources

Typically, BSC studies make use of known binding sites characterized by surface protein atoms surrounding an experimentally observed bound ligand.

We built a weight matrix describing the sequence preferences of Cbf1 from 16 Cbindingding sites characterized by Wieland et al.[18].[18]

Finally, we define a subset of GR binding sites characterized by minimal nucleosome remodeling that is highly enriched for non-enhancer and weak enhancer regions.

As explained in detail in the Results section, we also established the density of our motif in the high affinity binding sites characterized by Alekseyenko et al. [ 30] and Straub et al. [ 29].

This gene codes for a DGC of the type that is subject to I-site-mediated product feedback inhibition, since DgcX features an intact A-site (the enzymatically active centre with the GG(D/E EF motif) as well as an I-site (a secondary c-di-GMP-binding site characterized by an RxxD motif only 5 amino acids upstream of the A-site; Supplementary Fig S1).

We conclude that the presence of sites characterized by triple Insm1/Neurod1/Foxa2 binding is a predictor of Insm1-dependent gene expression.

This may be why most of the identified CNMS repeats were located in the orthologous and paralogous genes in the immediate upstream region (1 to 200 bp) of the transcription initiation site with preference for known regulatory binding sites as characterized by PLACE and PlantCARE (see Additional file 15).

The binding sites are characterized by imperfect packing, planar architectures, bridging water molecules, and, on average, smaller size.

The protein exists as a small monomer (148 residues), with four distinct calcium binding sites, each characterized by specific dissociation constants for calcium that vary between the low-affinity and high-affinity states [38].

The ligand binding site is characterized by a constrained size of the cavity and the requirement for both an acidic group and a hydrophobic group in the ligand (Fig. 3C).

The AR-like binding site is characterized by the highest affinity for T (IC50, 849 nM), followed by displacement effects about one order of magnitude lower for the androgen MT as well as for E2.