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Exact(8)
The remaining 5,873 set of non-redundant multi-exonic genes was binned based on read coverage.
For most of the nuwts, the copy number estimate based on read coverage was very close to the qPCR estimate.
Alternatively, tools based on read coverage can detect duplicated insertions of any length by finding reference segments that have higher read depth than expected.
Modified exon-intron structures and new putative transcripts were proposed based on read coverage, read splicing events and distance with respect to existing genes and transcripts.
Based on read coverage and SNP density, we identified 875 potential sex-chromosomal scaffolds with a total length of 19.5 Mb, comparable to the B. mori Z chromosome (20.35 Mb) (Arunkumar et al. 2009) (supplementary file S2, Supplementary Material online).
This could be addressed by exploring the depth of the aligned reads compared to an average; an analysis of differences in copy-number based on read coverage goes beyond the scope of our study.
Similar(51)
In the present work, we sought to identify the CCNV in T. cruzi strains belonging to different DTUs, based on read depth coverage of the 41 CL Brener chromosomes.
Read coverage was computed and genome annotation was challenged based on read distribution and coverage.
In addition, one can generate a taxonomic profile by quantifying the assigned reads, based on read counts or coverage for each individual bin.
Filtering may also be performed with a software program such as VarScan [ 17], an SNV caller which relies on read coverage, base qualities, and variant frequencies to separate true SNVs from errors.
Furthermore, we have a basic algorithm to derive a set of coordinates from DS data based on read counts or sequencing coverage.
Related(19)
based on read representation
based on read alignment
based on read pair
based on constructed coverage
based on read density
based on read count
based on read support
based on read recruitment
based on read abundance
based on read depth
based on read start
based on read mapping
based on read code
based on read mate-pairing
based on read speech
based on read quality
based on read length
based on shared coverage
based on read information
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