Sentence examples for mutations to provide from inspiring English sources

We used a semi-quantitative analysis that incorporated both the presence and clonality of all tested LOH mutations to provide an assessment of mutational load for a given microdissected target.

The analysis of mutation rates for 4 bp contexts analysis requires large amounts of mutation data (millions of inferred mutations) to provide statistically significant and biologically meaningful results.

We are continuing to analyse the remaining ten patients with this histological subtype for PGRN mutations to provide further support for this viewpoint.

Our view is that a score purporting to assess the likelihood of individual mutations to provide a somatic cell with an acquired advantage - and possibly give origin to a tumoral clone - must take this feature into consideration.

In conclusion, we used a functional comparative genomics approach that combines bioinformatics sequence examination tools to mapping and phenotypical analysis of human mutations, to provide novel information on the organization in repeated domains of sacsin.

AhpC/AhpD may be important in isoniazid-resistant strains where the catalase-peroxidase KatG has undergone mutation to provide a resistant phenotype [65].

We let r be the number of residues that can potentially complement the first mutation to provide the full two-residue adaptive feature.

The protein has an N-terminal hexahistidine tag for nickel chelate affinity purification, the D424A mutation to inactivate the 3′ 5′ exonuclease, the C907S mutation to remove the single native cysteine, and the L744C mutation to provide a unique labeling site on the fingers subdomain.

Invariably, protocol mistakes are made by introductory students in large classes due to class size and experience levels, but our model incorporates methodology that allows small lab groups of students to make the same mutation to provide "backups" for the other students in the section in the case that one team's experiment does not work.

However, those carefully performed experiments utilized a cell-based assay system encompassing HEK cells overexpressing the various PS1 mutants as well as human APP harboring a "Swedish" mutation to provide optimal amounts of the βCTF (β-carboxyl-terminal fragment of APP) substrate for γ-secretase, and it has been shown that increased levels of βCTF can further augment the Aβ42/Aβ40 ratio.

To facilitate the map-based cloning of genes underlying induced mutations and to provide templates for clone-based genomic sequencing, we have created a first-generation physical map of the medaka genome in bacterial artificial chromosome (BAC) clones.