Sentence examples for mutations to generate from inspiring English sources

We describe a simple and fast method that selectively uses ancestral mutations to generate a soluble, stable and functional variant of the target protein, here named sHPBP.

For example, the whole genomic potential of a plant species for biodiversity can be accessed by using gain of function mutations to generate a "functional genomics library" of mutant clonal cultures, and the bioactivity of these cultures tested by DSS.

We need those random mutations to generate innovation, especially breakthrough innovation.

In this study, we have optimized ODEC using consensus sequence design, cyclic permutation, and structure-guided mutations to generate a number of variants with improved yields, biophysical properties, stabilities, and affinities (KD of 10-50 nm) for various CD4bs targeting broadly neutralizing antibodies, including the germline-reverted version of the broadly neutralizing antibody VRC01.

Such targeted introductions of mutations to generate "knock-in" mutant mice, have recently been used to create models of ocular disease that closely mimic their human counterparts [19] [21].

Using mutations to generate neoplastic tumors has significant advantages.

Further, we employed the genetic algorithm operators such as crossover and mutation to generate the new regions of solution.

Instead of using cloning and mutation to generate new individuals, our algorithm builds a probabilistic model representing the joint probability distribution of the promising solutions and, subsequently, uses this model for sampling new solutions.

The initial population passes through the GA operators (selection, crossover and mutation) to generate new reservoir realizations.

We then combined both types of mutation to generate AcNgn3KO, which contains no canonical sites of ubiquitylation.

We then combined each DN transgene with the Ptp4E Ptp10doublele null mutation, to generate Ptp4E Ptp10D, Btl>RTK-DN embryos.