Sentence examples for mutations to accumulate from inspiring English sources

3) The enhanced efficacy of ribavirin at early time points could either be "due to a different mechanism of action or an additional antiviral activity" or the different mutational spectrum could render it less possible for adaptive mutations to accumulate.

This can cause these mutations to accumulate during continuous asexual growth, leading to strains with a high mutational load.

They then transferred the virus from one ferret to another, allowing more mutations to accumulate.

Interestingly, the evolution of cheaters, which destroy the cooperation dynamics, enables all the mutations to accumulate within one individual on a time scale that is much faster than with sequential evolution.

The failure of a cell to repair the defects in its DNA allows mutations to accumulate, some of which lead to tumour formation.

That is, longer intervals between speciation events allows more time for mutations to accumulate.

Mitochondrial DNA replicates frequently and independently of the cell cycle and mitochondrial DNA mutations tend to accumulate more than chromosomal DNA mutations because mitochondrial DNA lacks protective histones.

The results of our study showed that non-conservative mutations tend to accumulate in specific structural regions of the AL Vκ and Vλ sequences.

The remaining FAD mutations tend to accumulate distal to the γ-secretase cleavage site.

On the basis of the multistep model of carcinogenesis, several mutations need to accumulate for a cancer to arise.

Here we have shown that, at least missense mutations seem to accumulate largely neutrally (see Figure 5A).