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A deletion mutation converts a healthy copy of mtDNA to the mutant (unhealthy) variant.
A point mutation converts a proline residue at position 712 to histidine (P712H), thus rendering the receptor inactive [ 7].
This mutation converts a highly conserved serine to isoleucine within the second transmembrane domain of the ACTH receptor.
At the protein level, this mutation converts a highly conserved arginine 729 (Fig. 1B) into a tryptophan residue (p.R729W).
Mutation converts a cooperative allele to a non-cooperative allele and vice versa, and converts a recognition allele to one of the other (k – 1) possible alleles.
The U2006G (S221R) mutation converts an A U base-pair into an A G mismatch, while the C2011A (T223N) mutation converts a G C base-pair to a G A mismatch.
Similar(52)
This mutation converts an alanine to a valine at codon 225 and is associated with reduced enzyme activity and increased thermolability [ 1].
For 4CL1, one non-sense mutation was found in 6-9-G10 6-9-G10 6-9-G10tation converted a tryptophan to a stop codon.
en48 carries a missense mutation, converting an invariant residue (R63) that is crucial for PtdIns(4,5) P2-binding to alanine (Fig. 1F).
Now, an international team of biologists and their colleagues think they have found the answer: Over millions of years, genetic mutations converted a receptor that used to help hummingbird ancestors detect the savory umami taste into a receptor tuned to sweets.
We use the creation of implausible NAGNAG sites as a control, considering only mutations converting a non-AG into an AG dinucleotide (positions 2,3,5,6 in the pre-NAGNAG motif).
Related(19)
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