Sentence examples for mutation plays a from inspiring English sources

BRAF V600E mutation plays a negative prognostic role in metastatic colorectal cancer (mCRC), leading to a median Progression Free Survival (PFS) of 4 6 months with first-line conventional treatments.

Mutation plays a secondary role in the GA and tries to ensure potential solutions (individuals).

It is only where a gene is deleterious that mutation plays a major role in maintaining it in a population.

Especially, the I138L mutation showed relatively strong positive effects on both conversion steps in almost all mutant enzymes examined (Figure 5c), suggesting this mutation plays a key role in LinBMI-type activity.

Despite the recent and remarkable discovery that the JAK2V617F mutation plays a critically important role in the development of PV, much remains unknown about its pathogenesis.

These data, together with previous findings [9], [10], support the hypothesis that increased Ae. albopictus midgut infectivity resulting from the A226V mutation plays a primary role in enhanced viral transmission.

In order to avoid trapping in a local optimal solution and to ensure the search capability of a near global optimal solution, mutation plays an important role.

Taken together, our results in waxy maize seem to confirm that recurrent mutation plays an important role in crop domestication and genetic improvement.

Therefore, we conclude that gain-of-function USP8 mutation plays an important role in ACTH overproduction.

It has been proven that adaptive mutation plays an important role in the evolution of microorganisms [ 7].

Genetic testing to determine whether an individual harbors a deleterious BRCA1/ 2 mutation plays an important role in assessing risk and determining clinical management [ 10, 11].