Sentence examples for mutants indicating a from inspiring English sources
LIC4 overexpression suppresses the Li+-sensitive phenotype of calcineurin mutants but not the defect in recovery from pheromone arrest or viability of calcineurin dependent mutants, indicating a specific role in cation homeostasis.
The mRNA levels of several G1, but not G2, regulators change in scr mutants, indicating a peculiar role of G1 regulators in the RBR/SCR-mediated pathway that controls stem cell maintenance [73].
Under these conditions, the wild type strain and the bat1Δ mutant showed higher growth rates than those observed in the double and bat2Δ mutants indicating a catabolic role for Bat2 (Table 2 and Figure 1B, CEN).
Similarly, copulation attempts were absent in Est-6° mutants, indicating a decrease in courtship vigor.
The TcUGM variants displayed similar catalytic deficiencies as the corresponding AfUGM mutants, indicating a conserved role of these residues in the eUGM family of enzymes (Table 2).
In contrast, DROSHA was down-regulated in both the retina and RPE/choroids and DICER1 in RPE/choroids of erd mutants, indicating a dysfunctional miRNA metabolism.
Previous studies showed that expression of RLC-E20E21 could rescue the rough eye phenotype of Drosophila Citron mutants indicating an in vivo role for Citron in RLC phosphorylation [28].
Suppression of small RNA production from short repetitive sequences was also prominent in RdDM mutants, including dms4, drd1, dms3 and rdm1 mutants, indicating an equivalency with RNAP V.
Mean mIPSC amplitude was significantly increased in nrx-1 null mutants, indicating an increased number of functional UNC-49 receptors at synapses.
Notably, expression of hVAPB in flies rescues the lethality and the phenotypes associated with DVAP mutants, indicating an evolutionarily conserved function for VAP proteins (6).
Experiments using NICD1 deletion mutants indicated a role for the RAM domain in this process, and either Jagged1 stimulation or expression of a transcriptionally active form of RBP-J in 32D cells also promoted myeloid differentiation (Schroeder and Just, 2000).
