Sentence examples for multiple pathological states from inspiring English sources

They are also implicated in multiple pathological states, such as cancer, neurodegeneration and aging.

RIP3-mediated necroptosis has been demonstrated to be involved in multiple pathological states.

It has not yet been determined whether anisocytosis is the cause of the poorer prognosis observed among these patients or if it is simply a marker of multiple pathological states connected with said prognosis.

A decrease in variability is indicative of reduced adaptability, reflects a 'stressed' system [ 21, 22], and has been described as a marker of outcome in multiple pathological states, for example sepsis [ 22].

Despite the large increase of transcriptomic studies that look for gene signatures on diseases, there is still a need for integrative approaches that obtain separation of multiple pathological states providing robust selection of gene markers for each disease subtype and information about the possible links or relations between those genes.

Many clinical and biomedical studies look for the separation between multiple disease subtypes as distinct pathological states, but they are also very interested in finding the specific genes that are altered in each disease subtype.

The CXCR4 chemokine receptor is a seven transmembrane G-protein coupled receptor with multiple critical functions in both the normal and pathological states, having a sole natural ligand (CXCL12).

This molecule is critical for multiple physiological functions, yet plays a role in many pathological states, including neurodegenerative disease and cancer.

On the contrary, drug combinations, with multiple targets belonging to interlinked processes, can combat the systematic pathological states through the cooperative mechanism.

The authors argue that the existence of multiple equivalent molecular solutions for the transitions between the physiological and pathological states indicates the potential robustness of both of these states and explains, at least in part, the inefficiency of single-target drugs.

Despite associations with multiple pathological components, one hallmark of COPD is a persistent inflammatory state that contributes to a progressive decline in lung function [ 12].