Sentence examples for multiple gene conversion from inspiring English sources

The multiple gene conversion events that likely took place during the evolution of the extremely repetitive mouse Class B array [12], [21] precludes an accurate estimation of the sequence by which the cluster expanded.

While multiple gene conversion events can also result in the misleading appearance of a species-specific expansion, the more divergent Class A Mups form a distinct clade from the rat Mups and we find no evidence of gene conversion events in this class.

Third, it is possible that multiple gene conversion events harmonized the repeat structure after cod repeats amplification from the ancestral 9 repeat state.

Overall, the results clearly indicate that PGRST2 and PGRST3 subpopulations are modern M. tuberculosis lineages and emerged separately from PGRST1 strains through multiple gene conversion events.

Also, although the homogenization of the gene pairs could have been achieved by a single gene conversion event in each mammal, our evidence is more in line with multiple gene conversion events throughout evolution leading to concerted evolution of the gene pairs.

Therefore, gene conversion may potentially alter the relationships among paralogs and lead to the conclusion of independent duplications instead of multiple gene conversions in multiple species.

This result suggests that multiple gene conversions occurred in Region B, at least three times; once in the common ancestor of chimpanzees, gorillas and humans, once in an ancestor of gibbons, and once in the lineage of rhesus monkeys.

We have shown that the evolution of these paralogous genes has been affected by multiple events of gene conversion acting to homogenize among 5'UTR sequences, protein-coding sequences or both.

Levels of linkage disequilibrium (LD) and nucleotide divergence between inverted and standard chromosome arrangement change over time, and become reduced towards the middle of the inversion where multiple crossover and gene conversion are expected to be higher see [ 1], although this is not always the case (e.g., [ 18]).

Generally, if a protein is known to be encoded by multiple gene copies that undergo gene conversion or ectopic recombination, non-classical approaches to analyzing sequence polymorphism may need to be developed [46], [47], and it is possible that deeper sequencing of P. falciparum genomes will reveal this to be the case for more merozoite stage genes than has yet been appreciated [38], [39], [48].

These genes' sequences appear to have been homogenized by multiple episodes of interlocus gene conversion.