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Classifying these duplicated genes led to the discovery of multiple gene duplication events in different lineages, and insights into the origins of perforin itself.
There is evidence that many gene duplications are part of larger multiple gene duplication episodes, during which a large portion of an organism's genome is duplicated.
Subsequently, multiple gene duplication and paralog sorting events happened independently in different core eudicot taxa.
The presence of 20S proteasomes in bacteria may result from lateral gene transfer, while the diversification of subunits among eukaryotes is ascribed to multiple gene duplication events.
They are likely the products of single or multiple gene duplication in each specific species and are entirely different from the novel PRL2 reported in the present study.
Together, our data support the hypothesis that multiple gene duplication and gene 'loss' events have occurred during the evolution of the DIA1 family.
These analyses suggest an ancient gene duplication event, followed by fusion of these genes and divergence, then followed by multiple gene duplication events and divergence to create the different subunits.
From an evolutionary point of view, close localization and sequence conservation inside a cluster suggests that Cx. quinquefasciatus OBP gene family might have evolved by multiple gene duplication events followed by rapid diversifications, as already suggested for A. gambiae [21] and A. aegypti OBP families [23].
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Throughout this article we abbreviate the term 'multiple gene duplication episode' simply to 'episode'episode
One version of the multiple gene duplication problem was defined by Guigó et al. in 1996.
Subfamily B1-B4 AHLs emerged from lineage divergence events and further expanded via multiple gene duplication/loss/divergence events (Table 1).
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multiple gene activities
multiple gene variation
multiple gene copy
multiple gene cassette
multiple tandem duplication
multiple gene change
multiple gene function
multiple copy duplication
multiple gene modification
multiple gene transformation
multiple gene order
multiple gene expression
multiple gene delivery
multiple gene association
multiple gene microarray
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