Sentence examples for multiple agents targeting from inspiring English sources

Multiple agents targeting hepcidin and its regulators are under development as novel therapeutics for iron disorders.

As multiple agents targeting the IGF-IR are currently in early clinical trials, IRS expression should be considered as a potential biomarker for IGF-IR responsiveness.

In other therapeutic arenas, such as diabetes and hypertension, lower doses of multiple agents targeting different pathways often yield better results than strategies that modify one pathway alone.

Given these findings, multiple agents targeting IGF-IR have been developed, with several agents currently in early clinical trials (Garber, 2005).

This reflected trial design and clinical practice at a time when HER2-targeted therapy was not routinely continued in combination with successive chemotherapy regimens and there were not multiple agents targeting the HER family.

Just as combination chemotherapy in general has proven more effective in treating cancer than single agents, it might be wise to employ multiple agents targeting various components of the wound healing and inflammatory pathway to target cancer perioperatively.

Aberrant HGF/c-MET signaling via ligand dependent (both paracrine and autocrine) and ligand independent mechanisms is well documented in several human cancers [4], [5] and multiple therapeutic agents targeting this pathway are in clinical development [4] [6].

Because of this prominent role, multiple therapeutic agents targeting EGFR have been developed.

Since then, multiple new agents targeting this pathway have been developed and are in clinical use.

Therefore, within the near future pharmacologic treatment strategies may include multiple pharmacological agents, targeted simultaneously to block multiple pathways.

Multiple newer biologic agents targeting specific immune system pathways and effectors are undergoing evaluation [ 94].