Sentence examples for many agents targeting from inspiring English sources

The PI3K/Akt/mTOR pathway is now considered to be an attractive and promising target for cancer therapy and many agents targeting this pathway have been developed.

Intensive pharmaceutical efforts have generated many agents targeting histone deacetylases, and of these, currently two have received FDA approval, SAHA/Vorinostat (Zolinza) and FK228/Romidepsin (Istodax), and both are currently licensed for the treatment of cutaneous T cell lymphoma (Mann et al. 2007a; b; Hymes 2010).

Metabolic inhibitors represent an important class of anti-tumour agents and for many years, agents targeting the nutrient folate were developed for the treatment of cancer.

Considering the frequent mutation of K- ras in pancreatic cancer and its resistance to many anticancer agents, targeting NOX may have significant clinical implications and warrant further investigation.

Since the era of cytokine therapy, overall survival has now doubled, with the approval of many new agents targeting cell signalling pathways.

In this regard, the formation of these lesions would prevent the generation of the DNA strand breaks, which is a toxic effect of many therapeutic agents targeting cancer cells.

Many of these agents targeting HIF-1 are already in clinical trials.

Although cyclooxygenase has been the focus of many anti-neoplastic agents targeting the arachidonic acid pathway [ 185], other components of the pathway could potentially also be promising targets.

Therefore, BQZ decoction might be a better medication than many other biological agents targeting TNF-α, such as infliximab, etanercept, adalimumab, as the treatment of these agents does not halt new bone formation [ 25].

Moreover, many antimicrobial agents target macromolecule synthesis inside bacteria (Dodds, Grobe and Stewart 2000) during active metabolism.

As many therapeutic agents target only one of these types of markers, but still produce a reduction in, PFD seems to be a particularly valuable drug.