Sentence examples for more severe defect from inspiring English sources

However, the distinct pattern of mutant Tdp1 activity evident in yeast cells, suggests a more severe defect in Tdp1H432N-catalyzed resofution of 3′ phospho-adducts.

The lack of episomes in GM15808 suggest that their more severe defect in both NBS1 and MRE11contributes to their failure to support episomal maintenance of EBV.

Notably, a more severe defect was observed in the posterior peak of Hb expression (Figure 6B), that is normally positioned at 80 to 88% of EL [34].

A more severe defect in growth rate was observed for Tnhfq2, which took over fifteen hours to exit lag phase (Fig. 3B).

zmm mutants show decreased levels of crossovers at both 23 and 33°C, with a more severe defect at 33°C [16].

Since nuclear microtubules are essential for SPB separation [49], the spindle formation delay suggests a more severe defect in nuclear microtubule organization in tub4-S100E cells than in tub4-S74E tub4-S360D360D cells.

The spectrum of disorders generated by morpholino inhibition and the more severe defects (microphthalmia and anophthalmia) observed at higher doses illustrate the key role of GDF6 in ocular development.

A mutant lacking the periplasmic cytochrome MtrA demonstrated more severe defects.

Similar, but more severe defects were observed in K5-β1 skin (Figure 2A,B,E).

Many of the affected individuals are asymptomatic, but more severe defects may result in a fatal outcome if untreated.

Blocking of Wnt signaling using another transgenic line, hs:ΔTcf-GFP, resulted in more severe defects in swimbladder epithelium.