Sentence examples for more specific defect from inspiring English sources

Secondly, apoptotic responses following p53 activation and ER stress induction were normal, suggesting a more specific defect in macrophages compared to T lymphocytes in CD.

Another RRM-containing protein, TIAR, has a more specific defect, as it is required for survival of primordial germ cells and the formation of spermatogonia and oogonia, probably due to its effect on cell division [43].

The morphological changes we observe therefore reflect a more specific defect in the development of the brain and eyes, tissues in which OCRL1 is particularly abundant.

In summary, as shown in Figure 2 and Table S3, the vast majority of the hygromycin B-sensitive membrane traffic mutants were defective for uptake of Rb+, a more specific test of K+ defects than hygromycin B sensitivity.

Our alleged reclassification of defects in our Table 2 (Johnson et al. 2003) merely reflects careful reevaluation by the cardiologist and minor updates in terminology that mirror current clinical usage to clarify the nature of a defect (e.g., great vessel defect vs. the more specific aortic hypoplasia; L-transposition vs. abnormal looping, etc).

Because we did not identify general neuroanatomical defects, we investigated more specific aspects of the nervous system and identified defects in the HSN.

This topic is one of a number in which the GeneDB vocabulary had a general descriptor such as 'phenotype, cytokinesis defects' included as a substring of more specific entries such as 'phenotype, cytokinesis defects, contractile ring, absent', but the terms were not otherwise related.

PARP inhibitors target the DNA repair defect in a more specific fashion and are well tolerated without typical chemotherapy side effects [ 9].

This new compound appears to be the first of a (hopefully) large family of small organic molecules with a more specific inhibiting activity against the pathogenetic defects in leukemia as well as cancer.

We present only the results from analyses with more than five births among exposed infants with the specific defect or defect group.

The simplest possibility is that one or more specific alternatively spliced products are important for dendrite development and that defects in alternative splicing reveal defects in dendrite morphology (Olesnicky et al. 2014).