Sentence examples for modulator of breast from inspiring English sources

This complicates the ability to separate the relative importance of chemotherapy as a direct or indirect modulator of breast density.

The findings presented here suggest that GM3S expression is a multistep modulator of breast cancer cell metastasis.

Several recent reports from both global gene expression studies and mouse models indicate that the microenvironment may be a critical modulator of breast cancer progression.

In agreement with this latter study, recent findings of Coopman et al [ 2] showed that Syk is a potent modulator of breast epithelial cell growth.

The recent identification of Syk as a potent modulator of breast epithelial cell growth has generated a need for further exploration of the role of nonreceptor tyrosine kinases in breast cancer progression and metastasis.

However, data from randomised trials among postmenopausal women demonstrate that circulating levels of androstenedione and oestrone, important modulators of breast cancer risk, are lowest among women assigned to engaging in the most amount of overall activity [ 23- 25], suggesting that the amount of activity is more relevant than the intensity of activity, at least for reducing oestrogen levels.

WISP2 (WNT1-inducible-signaling pathway protein 2) gene expression is enhanced by important modulators of human breast cancer cell proliferation such as E2, progesterone, and epidermal growth factor.

Indeed, the potential role of the AhR in tumorigenesis has inspired the possible use of AhR modulators for breast cancer therapy [ 50].

The results obtained in BRCA1 full-length transfected cells suggest that the BRCA1 gene product is a key modulator of drug sensitivity in breast cancer cells in this specifc setting and add novel information as compared to studies performed on breast sporadic tumours.

From our modulator library an interesting inhibitor of breast cancer resistance protein (BCRP) was identified.

Insulin-like growth factor binding protein-3 (IGFBP-3) is an important modulator of development and progression of breast cancer as it regulates the amount of free, physiologically active IGF-I and IGF-II.