Sentence examples for modulator of chromatin from inspiring English sources

SIRT6 is a modulator of chromatin structure having an important role in healthy ageing, and there is a crucial need to find specific modulators for it.

p300 is a histone acetyltransferase which functions as a modulator of chromatin structure [17], [18].

PARP3 is structurally related to the well studied PARP1, a modulator of chromatin structure that plays important roles in the DNA damage response, cell death signaling and transcriptional regulation, and to PARP2, that is also involved in the maintenance of genomic integrity (reviewed in [1], [2]).

Histone acetylation is a modulator of chromatin structure involved in DNA replication, DNA repair, heterochromatin silencing and gene transcription [ 1, 2].

In addition to its role as a modulator of chromatin structure to control gene expression, PARP-1 has also been shown to act as classical transcription factor-dependent coregulatory protein.

In a landmark study, Peterson and co-workers harnessed histone semisynthesis to investigate the biophysical and biochemical consequences of acetylating H4K16, a key modulator of chromatin structure and function in development and disease.

Reeves R. High mobility group (HMG) proteins: Modulators of chromatin structure and DNA repair in mammalian cells.

Molecules that bind to the nucleosome, the complex of DNA and histone proteins, are key modulators of chromatin structure.

They also might play a role in other processes, e.g. as repressors, replication origins or modulators of chromatin structure.

The second possible connection between dosage compensation and general modulators of chromatin state is the chromatin remodeling factor ISWI.

Two proteins relatively more abundant in male gametocytes co-purified with FACT both of which contain ALBA domains which are highly conserved modulators of chromatin structure (Fig. S1).