This suggests that novel experiences are powerful modulators of plasticity even in the adult brain.
Motivation and attention can be critical modulators of plasticity.
Salience, motivation and attention can be critical modulators of plasticity (Woldag and Hummelsheim, 2002; Nithianantharajah and Hannan, 2006; Kleim and Jones, 2008).
This reflects a given modulator effect of plasticity on both robustness and evolvability.
Our data confirmed the suggestion that VEGF may be a potent modulator of neural plasticity in the LUT.
This novel action of CXCL12 is not only consistent with a critical role of the CXCL12/CXCR4 axis in neuroprotection, but further expands the potential of CXCL12 as a modulator of synaptic plasticity in the context of epigenetic mechanisms.
For instance, overexpression of neurotrophic nerve growth factor (NGF), a well-known modulator of neural plasticity, in the urinary bladder of mice caused bladder hyperreflexia associated with increased voiding frequency [ 7, 52].
The high total and saturated fat diets found in this sample have been associated with reduced hippocampal levels of neurotrophic factor, a crucial modulator of synaptic plasticity [ 27], which can induce cognitive dysfunction [ 28].
The VEGF pathway is being proposed as a key modulator of neural plasticity in the pelvis and enhanced VEGF content may be associated with visceral hyperalgesia, abdominal discomfort, and/or pelvic pain.
Group II metabotropic (mGlu II) receptor subtypes mGlu2 and mGlu3 are important modulators of synaptic plasticity and glutamate release in the brain.
