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SNP309 was thus postulated as a potential modulator of cancer susceptibility [ 11].
Recent studies have shown that thrombin might also be an important modulator of cancer metastasis in vivo.
A common A/G polymorphism described as a modulator of cancer risk is thought to regulate the production of cyclin D1b [ 4].
For example, WW domain-containing oxidoreductase (WWOX), as a modulator of cancer metabolism, via its first WW domain, physically interacts with HIF1 α and modulates its levels and transactivation function.
Similar(56)
Many cancers meet their blood supply demands by inducing angiogenesis, and there is increasing evidence implicating integrin signaling, generated by interactions with ECM proteins and with VEGFR, as a major modulator of cancer-induced angiogenesis [ 4, 11].
Tariquidar (XR9576) analogs, modulators of cancer multidrug resistance (MDR), were subjected to QSAR and 3D-QSAR analyses.
Dieldrin exposure also altered the expression of BNDF and TrkB, novel modulators of cancer pathogenesis.
Dependence receptors were initially identified in cancer biology as important modulators of cancer progression.
The high frequency of NAT1 acetylators genotypes are important modulators of cancer susceptibility [ 55].
Neutrophils are garnering attention as important modulators of cancer progression [ 17- 20].
Many microRNAs function as oncogenes, tumor suppressors, or modulators of cancer stem cells and metastasis.
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