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The orexigenic gut hormone ghrelin is an important central modulator of energy intake[17].
The orexigenic gut hormone ghrelin is an important modulator of energy intake[17].
Thus, variations in the UCP2 gene was proposed as potential modulator of energy balance.
These results suggest that proNMU104-136 is a novel modulator of energy balance and may contribute to the phenotype exhibited by NMU knockout mice.
These results suggest that proNMU104-136 is a novel modulator of energy balance and, given the extreme sequence conservation of this peptide, may be an important factor in human metabolic regulation.
Our results show that this peptide, which is well conserved between human, mouse, and rat (Table 1), has a pronounced effect on energy balance in mice and may be a novel modulator of energy balance.
Similar(54)
Our work opens up the possibility of using modulators of energy metabolism to control neuronal plasticity in diseases and conditions of aberrant plasticity such as epilepsy.
Besides the melanocortin system, some other circulating hormones are thought to play an important role as modulators of energy flow within the organism.
NAD(H) is considered a key modulator of cellular energy metabolism [ 53, 54].
The overall effect is to reduce mitochondrial function while enhancing anaerobic metabolism, suggesting that Txnip is a key modulator of myocardial energy homeostasis (48).
In summary, tribbles-1 is an important modulator of human energy metabolism and metabolic syndromes and worthy of future studies aimed at investigating its potential as a therapeutic target.
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