Sentence examples for modulating the affinity from inspiring English sources

Oligosaccharides attached to Asn297 in each of the CH2 domains of monoclonal antibodies play an important role in antibody effector functions by modulating the affinity of interaction with Fc receptors displayed on cells of the innate immune system.

Cells control adhesion via integrins by regulating the amount of integrins expressed on the cell surface and also by modulating the affinity of integrins to their substrates.

Elated RAS viral (r-ras) oncogene homolog (RRAS) was considered to regulate the progression of dedifferentiation by modulating the affinity and avidity of α5β1 integrin to ligands.

The concentration threshold for phase separation can be tuned by modulating the affinity of the interactions that promote phase separation (e.g., through posttranslational modification of proteins), thus altering the concentration of macromolecules in free solution.

By describing the mechanism of BubR1 recruitment and the role of the loop motif of Bub1 and BubR1 in modulating the affinity for kinetochores, this study fills an important gap.

Our data on PC3 and TRAMP cell migration on various ECM proteins, as well as the effect of changes in Akt1 activity in modulating the affinity of PC3 cell-surface integrin αv β3 on its specific ligands, such as vitronectin, fibrinogen and WOW-1, demonstrate that Akt1 activity is necessary for the affinity modulation of integrin αv β3.

The polarization term was found as the most relevant to modulate the affinity of each ligand for the metal center.

Furthermore, PCL was shown not only to toughen the epoxide but also to modulate the affinity of the matrix to the fiber.

Sialic acid binding is shown to trigger a conformational switch that modulates the affinity for the acceptor substrate and concomitantly creates the conditions for efficient transglycosylation.

It remains to be studied whether in reverse, Chordin/CV2 binding also modulates the affinity between CV2 and BMPs.

By assaying several β-carboline compounds, we define certain chemical groups that modulate the affinity of this class of compounds for inhibition of tau phosphorylation.