Sentence examples for affecting the affinity from inspiring English sources

This effect could either be due to steric hindrance, or a conformational change affecting the affinity for ATP.

Iso-OMPA is an effective organophosphate inhibitor of BChE but not AChE [52], where it is over 10,000 times less reactive [14], and this selectivity appears dependent on the dimensions of the active center of the enzyme, particularly the acyl pocket, affecting the affinity of the enzymes for inhibitor.

This could be achieved experimentally by making amino acid substitutions or deletions on TetR2 [ 60], thereby affecting the affinity of Tc for TetR2.

Functional polymorphisms on two FcR genes (FCGR2A, FCGR3A) affecting the affinity of FcR for fragment C have been identified [ 37, 38].

A characteristic of dynasore is the non-competitive inhibition of the basal and stimulated rates of GTP hydrolysis, without affecting the affinity for GTP binding or dynamin self-assembly [ 2].

The expression pattern of MEIS1, its contribution to pinopode formation in mouse and its effect on Itgb3 expression suggest that the effects of MEIS1 on endometrial function occur through affecting the affinity and specificity of HOXA10 DNA interactions, leading to the regulation of downstream targets of HOXA10.

Conversely, binding of these substances to hemoglobin affects the affinity of hemoglobin for oxygen.

In this way sodium binding events in sites Na+1 and Na+3 not only interlink with each other, but also strongly affect the affinity for aspartate.

In our kinetic experiments, this deletion did not affect the affinity of protoporphyrinogen IX nor the FAD content, but decreased the catalytic efficiency of the enzyme.

A single point mutation at position 131 replace an arginine (R) with a histidine (H) that can affect the affinity of the receptor for human IgG subclasses.

The addition of L-Gln during the reaction did not affect the affinity for the substrate or the degree of cooperativity for ScASNase1 (Table 1 and Fig. 2A,B), which is different from that recently described for EcASNase2 and reveals distinct functional characteristics of the yeast enzyme.