Exact(3)
The prediction follows that treatment of the RIP1-Tag2 mice with pan-Bcl inhibitors will disrupt tumor growth if indeed, (as expected) these genes cooperate in modulating the propensity for apoptosis as an intrinsic barrier to tumorigenesis.
Additionally, previous work indicated that Ku70 mediates a feedback loop selectively modulating the propensity toward apoptosis or cell cycle progression/survival.
The use of this marker made it possible to study the effects of several factors modulating the propensity of different cell types to undergo senescence, such as suppression of metabolic activity by 2-deoxy d-glucose (2dG), capacity to continue cell growth (synthesize RNA), and importance of cell cycle phase.
Similar(5)
Any process that modulates the propensity of RNA molecules to degradation.
An other result of our modeling approach leads to the conclusion that the 'group size effect' is extremely robust in respect to variations in the parameter values that modulate the propensity to imitate and the duration of both scanning and foraging activity.
This N-terminal conformational change may modulate the propensity of PrP aggregation since this region influences the amount of secondary structure in the remainder of the molecule [ 49].
Because these intrinsic tempos also clearly affect the risk of failing to detect a predator, determining how individual characteristics modulate the spontaneous propensity to switch activity (i.e. k parameter values) remains an exciting theoretical and experimental challenge.
However, when investigating the dynamical features of risky situations, we show that collective vigilance is strongly influenced by the absolute parameter values that modulate the respective propensity to imitate conspecifics in foraging and scanning decisions (εF and εS) and the activity transition rates (kF and kS).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com