Sentence examples for modulating inflammation in from inspiring English sources

Taken together our data reveal that enteric neurons producing NPY play an important role in modulating inflammation in colitis.

Although we have shown that CR manages tumor growth and improves survival through multiple molecular and biochemical mechanisms, little information is known about the role that CR plays in modulating inflammation in brain tumor tissue.

KCs or resident hepatic macrophages carry out an important role in modulating inflammation in liver fibrosis development [ 7- 9].

Interestingly, halofuginone is known to inhibit specifically Th17 cell differentiation [ 101], suggesting that this molecule might act by modulating inflammation in the dystrophic muscle.

Cholinergic anti-inflammatory pathway (CAP) bridges immune and nervous systems and plays pleiotropic roles in modulating inflammation in animal models by targeting different immune, proinflammatory, epithelial, endothelial, stem, and progenitor cells and signaling pathways.

As the Notch pathway is easily amenable to pharmacological manipulations such as γ-secretase inhibitors and metalloprotease inhibitors, targeting Notch signaling may represent a new and promising approach to modulating inflammation in relevant disease states.

Poly adenosine diphosphate (ADP) ribose polymerase (PARP) activity is known to modulate inflammation in animal models of injury.

Besides driving the propagation of pain signals, spinal mechanisms are also discussed to modulate inflammation in the periphery.

These findings open a new line for further investigations which could result in a new way to modulate inflammation in chronic migraine.

The aims of this study were to modulate inflammation in synovial explants with the compounds: dexamethasone, rapamycin, bone morphogenetic protein 7 (BMP-7) and pravastatin, and to investigate the modulatory capacity of the compounds on specific macrophage phenotypes.

In summary, this study shows that HSP70 can modulate inflammation in a model for chronic and progressive arthritis through IL-10 dependent mechanisms, operating via suppression of pathogenic antibody responses and the development of regulatory T cells.