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We have developed a novel, low-cost device designed to monitor and modulate locomotor activity in murine subjects.
Both OA and TA appear to modulate locomotor activity in the larva [65], [66] and in the adult fly [67], [68].
The vmTH neurons send their primary neurites dorsally and then project through the dorsal part of the neuropil above TP 3. Since the dorsal neuropil comprises the dendritic compartments of most motoneurons [19], vmTH neurites are ideally located to modulate locomotor activity.
Estrogens are known to modulate locomotor activity in rodents (Ogawa et al. 2003).
Several factors such as age and sex of animals can modulate locomotor activity of mice and could explain the differences between our and previous studies [49].
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Furthermore, the aging-related loss of DA in the SN, rather than striatum, in conjunction with a significant decline in locomotor activity in the 30-month group supports a role for nigral DA tissue content in modulating locomotor activity generation.
Tyrosine hydroxylase (TH) is the rate-limiting enzyme of DA synthesis in the midbrain dopaminergic neurons of the ventral tegmental area (VTA) modulating locomotor activity and reward.
In view of evidence that the BRAS modulates locomotor activity and cognitive performance, we tested the effects of drugs that target the BRAS on these behaviours in NK1R−/− and wildtype mice.
Thus, both TDC2 neuron groups may interact to modulate larval locomotor activity.
However, in rats both the power and the frequency of the theta rhythm are modulated by locomotor activity, which is a major confounding factor when estimating its cognitive correlates.
This remarkable tropism of Dengue virus for the insect nervous tissues led us to hypothesize that the infection might have some role in modulating the vector locomotor activity behavior, since it is known that activity rhythms in Drosophila and other Diptera are regulated by circadian clock neurons in the brain (reviewed in [24],[24]).
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modulate miRNA activity
modulate p53 activity
modulate channel activity
modulate polymerase activity
modulate macrophage activity
modulate promoter activity
modulate brain activity
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influence locomotor activity
regulate locomotor activity
modify locomotor activity
alter locomotor activity
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