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As shown in Figure 2, the AG129 mice were sensitive to the virus at varying degrees based on the viral inoculum, with disease progressing slowly and animals first succumbing on day 10 of infection.
Moreover, tumours from these mice were sensitive to MEK inhibition.
Aachoui et al. revealed that the caspase-11 knockout mice were sensitive to infection by cytosolic bacteria, but resistant to LPS sepsis.
These mice were sensitive to CCl4-induced liver injury and displayed increased levels of hepatic necrosis (Fig. 5H K) with significant morbidity occurring within 2 weeks (Fig. 5L).
Jnk1 KO mice were sensitive to lung metastasis of B16F0 melanoma and EL-4 thymoma cell lines injected i.v. because the cytotoxic functions of CD8+ T cells were suppressed.
In an in vitro study, mouse fibroblast cells from Mrp7 knockout mice were sensitive to several natural anticancer drugs such as docetaxel, paclitaxel, vincristine, and Ara-C, confirming the previously characterized resistance profile of MRP7 [97].
Similar(51)
In the present study, we confirmed that BALB/C mice are sensitive to ADR-induced nephropathy, while C57BL/6 mice are resistant to such damage.
Taken together, these data reveal that synaptic protection in the CNS of WldS mice is sensitive to gene-dose.
Thus Leptin145E/145E mice are sensitive to the exogenous administration of wild-type leptin, suggesting the mutant V145E leptin is not functional.
It has been shown that the T17M RHO mice are sensitive to light.
Rats and mice are sensitive to hepatocellular hyperplastic effects of PPARα ligands.
Related(20)
studies were sensitive
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babies were sensitive
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mice were heterozygous
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mice demonstrated sensitive
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