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BALB/c mice were sensitized intradermally with 0.1 ml of 3% TMA or 0.3% OA in corn oil followed by intratracheal instillation with TMA conjugated to mouse serum albumin (TMA MSA; 30 or 400 μg) or OA (30 μg).
HLA-DQ8/HCD4 mice were sensitized with gluten, and gavaged with indomethacin plus gluten.
Six-eight weeks old female mice were sensitized with RWE as previously described [35].
The mice were sensitized on day 0, and on day 14, with intraperitoneal (i.p).
Moreover, the mice were sensitized intraperitoneally, which may have biased the response somehow to the viscera.
WT Balb/c, IFN-γ KO or FcγRIIb KO mice were sensitized by two intraperitoneal (i.p).
Alternatively, mice were sensitized with 2×106 HDM-pulsed, bone marrow-derived mDCs.
Two weeks later, the mice were sensitized to protein extracts from MON810 or the non-GM counterpart.
C57Bl6 wild type (WT) and C57Bl6 FcγRIIb knock-out (KO) mice were sensitized and then challenged with RWE.
Functional characterization of MMP8 revealed that mmp8−/− mice were sensitized to ventilator-induced lung injury with increased lung vascular permeability.
On day 0 NOD mice were sensitized with 100 µg of chicken egg OVA (Sigma-Aldrich) in 1.6 mg aluminium hydroxide i.p. in a volume of 200 µl.
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