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Fetal mice were genotyped using yolk sac DNA and adult mice were genotyped using tail DNA as template for PCR.
F1 agouti mice were genotyped by PCR.
Chimeric founder mice were genotyped by PCR.
All available irradiated and un-irradiated mice were genotyped.
Cohort 1 mice were genotyped using the Illumina Medium Density Linkage panel (MDL).
All mice were genotyped by PCR using DNA isolated from tail snips.
All mice were genotyped from ear punch biopsies as previously reported [40], [41], [42].
Embryos and newborn mice were genotyped by PCR analyses (Fig. 1C,D) using allele-specific primers.
Heterozygous mice were used as breeding pairs, and all mice were genotyped by PCR.
These mice were genotyped by PCR of DNA isolated from ear punching.
Cohort 2 mice were genotyped using a custom designed SNP panel (IP).
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