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Next, we asked whether T cells in the synovial fluid of inflamed ankles of SCID mice were detectable by flow cytometry.

Changes in marrow cellularity of collagen X Tg and KO mice were detectable both histologically and by flow cytometry.

The pancreas of both wild-type and Dicer1-hypomorphic mice developed normally and endocrine and exocrine cells appeared morphologically normal at E15.5 and P1 (Fig. 6A, B); the same abnormalities observed in adult Dicer1-hypomorphic mice were detectable at 4 weeks of ages (Fig. 6C), although the number of abnormal cells was less than that found in adult Dicer1-hypomorphic mice.

Deleted mtDNA signals in the frontal lobe, posterior cortex, and hippocampus of Polg +/D257A mice were detectable after overexposure in Southern blot analysis, same as is shown in Figure 2B, but were not detectable at all in Polg +/+ mice (Fig. 3A, lower panel).

Levels of malondialdehyde (MDA), a marker of oxidative stress, doubled in response to STZ treatment; however, no significant differences between STZ-treated wt and flip−/− mice were detectable (wt versus flip−/−, 3.4 versus 2.7 nmglivermg liver tissue; P=NS, data not shown).

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We assume that the observed striatal transcriptome changes are secondary effects of compromised DA signaling through nigrostriatal A53T-SNCA overexpression since human SNCA immunoreactivity in the striatum of PrPmtA and PrPmtB mice is detectable only in synapses, but not in neurites or cell bodies [13].

The motor deficit in N171-Q82 mise is detectable at 10 11 weeks of age (Schilling et al., 1999).

Tumor growth in intact mice was detectable 4 weeks post-implantation using BLI with an average luminescence intensity of 2 × 10 photons/second.

YopM-Cy5 injected into the hind paws of hTNFtg mice was detectable in the joint without a systemic distribution for 48 hours and elimination mediated through renal clearance.

PSI-induced loss of dopaminergic neurons in PLP-hαSYN transgenic mice was detectable 2 weeks after treatment (28%%) and progressed up to 54 % neuronal loss at 12 weeks.

Our findings in this study are congruent with these data: a very small number of transferred T- and B-lymphocytes derived from either control or glaucomatous mice are detectable in the ganglion cell layer of recipient mice.

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