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The MCS stands as a likely candidate to mediate the behavioral, hormonal and metabolic consequences of nutritional manipulation [24].
TRNs mediate the behavioral response to light touch (Chalfie, 2009).
These results demonstrate that honey bee genomic responses to immunostimulation are substantially broader than the previously identified canonical immune response pathways, and may mediate the behavioral changes associated with social immunity by orchestrating changes in chemical signaling.
This nucleus is the main source of amygdala outputs to the brain stem and hypothalamic sites (Holstege et al. 1996) that mediate the behavioral and autonomic responses associated with fear (LeDoux et al. 1988; De Oca et al. 1998).
To begin dissecting which neurons in the Gr66a expression pattern mediate the behavioral responses to lobeline, we assayed Gr66a GAL4/+ UAS-Shi ts/+ females that also carried teashirt-GAL80 (TSH{GaL80}), a GAL4 repressor with expression in the thorax and legs (J. H. Simpson, unpublished data; Clyne and Miesenböck 2008).
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To test whether ppk23 plays a role in mediating the behavioral response to CH503, we examined the behavior of male flies in which ppk23 expression was silenced using RNAi.
Activation of neurons in the anterolateral bed nucleus of the stria terminalis (BNSTALG) plays an important role in mediating the behavioral response to stressful and anxiogenic stimuli.
P. Bushnell proposed a pathway linking the neural targets and cellular to behavioral effects of acute exposure to organic solvents, whose predictive power is limited by our incomplete understanding of the complex CNS circuitry that mediates the behavioral responses to solvents.
In addition to modulating 5-HT neuronal activity, CRFR2 stimulation mediates the behavioral aspects of this process (70).
Thus, in contrast to our findings with the NPF peptide, the product of the TK gene is necessary for mediating the behavioral actions induced by CH503.
Similar to what was observed for the DA experiments, the effects of HCRT manipulations appear to extend beyond stimulant self-administration since previous work shows an involvement of HCRT in mediating the behavioral effects of nicotine, opiates, and ethanol.
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