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To test whether ppk23 plays a role in mediating the behavioral response to CH503, we examined the behavior of male flies in which ppk23 expression was silenced using RNAi.
Activation of neurons in the anterolateral bed nucleus of the stria terminalis (BNSTALG) plays an important role in mediating the behavioral response to stressful and anxiogenic stimuli.
Thus, in contrast to our findings with the NPF peptide, the product of the TK gene is necessary for mediating the behavioral actions induced by CH503.
Similar to what was observed for the DA experiments, the effects of HCRT manipulations appear to extend beyond stimulant self-administration since previous work shows an involvement of HCRT in mediating the behavioral effects of nicotine, opiates, and ethanol.
We interpreted these data as suggesting that ppk23-expressing GRNs were mediating the behavioral response of males to aphrodisiac CHCs, which was further confirmed by the reduced behavioral response of ppk23 mutant males to the excitatory pheromone 7,11-heptacosadiene (7,11 HD) (Lu et al., 2012; Thistle et al., 2012).
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P. Bushnell proposed a pathway linking the neural targets and cellular to behavioral effects of acute exposure to organic solvents, whose predictive power is limited by our incomplete understanding of the complex CNS circuitry that mediates the behavioral responses to solvents.
The MCS stands as a likely candidate to mediate the behavioral, hormonal and metabolic consequences of nutritional manipulation [24].
TRNs mediate the behavioral response to light touch (Chalfie, 2009).
In addition to modulating 5-HT neuronal activity, CRFR2 stimulation mediates the behavioral aspects of this process (70).
These results demonstrate that honey bee genomic responses to immunostimulation are substantially broader than the previously identified canonical immune response pathways, and may mediate the behavioral changes associated with social immunity by orchestrating changes in chemical signaling.
The time course for the expression of the IEGs c-fos and Egr1 does not support de novo gene transcription as being responsible for mediating the acute behavioral effects of pyrethroids.
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mediate the behavioral
mediating the glutamatergic
mediating the enhanced
mediating the social
mediating the financial
mediating the salutary
mediating the anti-tumor
mediating the initial
mediating the aversive
mediating the vascular
mediating the online
mediating the rewarding
mediating the cellular
mediating the physical
mediating the high
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