Sentence examples for mediate the actions from inspiring English sources

Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the actions of the thyroid hormone (T3) in development, growth, and differentiation.

The effects of GPR120 activation on BAT activity and WAT browning appear to mediate the actions of omega-3 PUFAs, which are physiological activators of the GPR120 receptor, on these processes.

At least three G-protein-coupled receptors (for review, see Branchek et al. 2000) mediate the actions of galanin, of those GalR1 mRNA is found exclusively in the CNS and PNS, whereas GalR2 and GalR3 are expressed also in other organs (Waters and Krause 2000).

Our TAK1 inhibitor program (discovered with the Derbyshire Laboratory, Department of Chemistry, Duke) has defined a highly potent and selective inhibitor of TAK1 kinase an important protein kinases thought to mediate the actions of proinflammatory cytokines such as TNFa, IL1 and TGFb.

Several receptors displayed on the cell surface can mediate the actions of PGE2 [29].

Further, it is shown that distinct signalling pathways mediate the actions of soluble Aβ on Homer1b and Shank levels.

Type I cytokine receptors mediate the action of the members of the long chain cytokines canonically involved in numerous physiological function.

Pharmacological studies suggest PACAP receptor subtypes might mediate the action of systemically administered PACAP.

We examined whether AMPK can mediate the action of leptin in the intestine.

The nAChRs are ligand-gated ion channels that mediate the action of acetylcholine at neuromuscular junctions and between neurons.

One of the characteristic functions of AhR is to mediate the action of dioxin to induce cellular inflammatory responses [ 23].