Sentence examples for mediate the role from inspiring English sources

FGL2 prothrombinase expression may mediate the role of thrombin in human parturition.

Future research should evaluate whether these mechanisms mediate the role of arsenic in diabetes development.

ROS have been shown to mediate the role of Rac1 in actin cytoskeleton reorganization [ 28].

Psychosocial, material or behavioural characteristics did not mediate the role of extreme living conditions on oral health.

The fact that expression of Bcl-xL blocked the apoptotic effects of the adenovirus in lung injury suggested that Bcl-xL may mediate the role of STAT3 in the regulation and survival of the respiratory epithelium [ 13].

Several p53 target genes have been identified to mediate the role of p53 in maintaining mitochondrial oxidative phosphorylation, including SCO2 (synthesis of cytochrome c oxidase 2), AIF (apotosis-inducing factor), GLS2 (glutaminase 2), Parkin and p53R2.

We next addressed whether specific neuron types within the Drosophila brain would be of particular importance in mediating the role of autophagy in protecting aversive olfactory memories.

However, overstory composition (covertype) appears to have a higher order influence on vegetation and mediates the role of topography.

The molecular factors mediating the role of nerves have begun to emerge, but interestingly it appears that they differ between systems: while the secreted protein nAG is sufficient to rescue the loss of nerves in salamander limbs, it is unlikely to play a major role as a nerve-derived factor in other species46,47.

Phosphoinositide-3 kinase (PI3K /AKT signaling regulates several important functions in cells, such as cell growth, proliferation, migration and apoptosis.45,​46,​47 Upregulation of IAPP promoted PI3K expression in our experiments, indicating that PI3K/AKT pathway mediated the role of IAPP in regulating apoptosis of NP cells.

To this end, it will be interesting to further investigate genetically whether Gdf5/Bmp signaling control initiation chondrocyte hypertrophy by antagonizing PTHrP signaling and whether Gdf5/Bmp signaling also mediates the role of Wnt/β-catenin signaling in hypertrophic chondrocyte maturation.