Sentence examples for mediate the full from inspiring English sources

Furthermore, our observations revealed that both contact-independent and contact-dependent factors are required to mediate the full cardiogenic potential of the endoderm.

Therefore, permanent direct interaction between the host and the pathogen is crucial for a complete lethal effect i.e. the killing of worms requires living or proliferating B. pseudomallei to continuously produce toxins in order to mediate the full killing effect.

Hence, dFOXO-dependent and dFOXO-independent processes may mediate the full effects of reduced IIS on oogenesis.

Therefore, signaling via both dFOXO and Ras/Mapk may together mediate the full IIS response during oogenesis.

Taken together, these results show that a threshold of endogenous RanBP9 is required to mediate the full deficits in hippocampus-dependent contextual memory but not cued memory.

In conclusion, our data suggest that there is evolutionary divergence in the downstream effectors of IIS, and so in higher organisms, additional factors may act in concert with FOXOs to mediate the full response to reduced IIS.

This opens up the possibility that ghrelin itself is not the ligand mediating receptor activation to promote food anticipatory activity and that there is another ligand of the ghrelin receptor that mediates the full expression of FAA.

We find that Tyk2 is essential for mediating the full LPS response and for baseline expression of IFN-inducible genes, but not for the LPS-induced upregulation of IFN-responsive genes.

Activation of NF-κB and MAPK pathways lead to transcription and mRNA stabilisation of pro-inflammatory molecules; transcription factors such as AP-1 and c/EPB are also important in mediating the full activities of IL-17 (reviewed in [ 138]).

It seems that the addition of the hydrophobic ZnPcs counterbalances the effects of PAMAM dendrimers on the atheromatous carotid tissue, suggesting that both the surface type and the drug composition mediate the drug delivery efficiency, in full agreement with previous nanothermodynamic studies of nanoparticles on surfaces [28,83].

Remember, a victim of bullying often feels intimidated by the aggressor, so your attempts to get the full story or to mediate the situation will not be productive.