Sentence examples for mediate the cellular from inspiring English sources

These proteins could mediate the cellular uptake of siRNA in vitro, though compared with PTD-DRBD gene silencing was attenuated by endosomal entrapment.

Gene-specific transcription factors are DNA binding proteins that function at the center of the transcriptional machinery to mediate the cellular phenotype in response to extracellular signals.

Background: 14-3-3 proteins abundantdand and conserved polypeptides that mediate the cellular effects of basophilic protein kinases through their ability to bind specific peptide motifs phosphorylated on serine or threonine.

Our study suggests that multivalent ligand-dendrimer conjugates may act as a unique type of artificial factors to mediate the cellular microenvironment in 3D culture, a property attributable to the spatial organization of the ligands and possible "cell-gluing" function of multivalent conjugates.

However, additional family members are now known to mediate the cellular uptake of amino acids and their derivatives in a number of tissues [20], [21].

In animals, RfBP functions to mediate the cellular translocation of riboflavin [ 60, 61].

The MRP1 mediates the cellular efflux of various xenobiotics including heavy metals and mediates cellular resistance to heavy metals.

The major transcription factor, which mediates the cellular response to hypoxia, is hypoxia-inducible factor (HIF).

Our observations identify a new role for syndecan-1 in mediating the cellular interactions and fate of positively charged submicrometer amorphous silica particles in the alveolar type II epithelial cell, a target cell for inhaled particles.

These results indicate a decisive role of NMDA receptors in mediating the cellular effects of UCB.

The role of autophagy in mediating the cellular response to stress has been examined by interferencing the expression of mammalian orthologues of the ATG gene [10].