Sentence examples for mediate the physiological from inspiring English sources

BACKGROUND: Swine contain large numbers of pulmonary intravascular macrophages (PIMs) that mediate the physiological response observed in acute lung injury (ALI).

The adrenergic receptors (ARs) (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine.

These unexpected targets could, in some cases, mediate the physiological effect of a drug, even if the drug is designed specifically to target one particular protein [2].

Further, there are proteins – so called effectors – that are assumed to mediate the physiological response of the pathway in their active state.

In addition to A β, the ectodomain of APP has been reported to have neuroprotective effects and mediate the physiological functions of APP.

In contrast, GRs, because of their lower affinity for the ligand, respond to high levels of glucocorticoids to mediate the physiological recovery from stressful events and restore the system to homeostasis [ 155, 159].

Moreover, they likely arose from a common ancestral receptor gene and subsequently diverged through gene duplication and chromosomal duplication to perform their distinctive roles in mediating the physiological effects of catecholamines.

To our knowledge, this represents the first observation of miRNA mediating the physiological action of a hormone in the development of the liver.

Corticotropin-releasing factor (CRF) is involved in mediating the physiological and behavioral responses to stress [ 1- 5].

Guanine nucleotide binding protein (GNAO1) mediates the physiological effects of various neuronal receptors [ 35].

It was also hypothesized that ghrelin mediates the physiological responses of tissues which surround the tumor, to malignant changes [ 34].